Mercedes-Benz CLS550 — All Years
| Year | Engine | Fuel | MPG (UK) | NHTSA |
|---|---|---|---|---|
| 2018 | 4.7L 8-cyl | Premium Gasoline | 25 | — |
| 2017 | 4.7L 8-cyl | Premium Gasoline | 25 | — |
| 2016 | 4.7L 8-cyl | Premium Gasoline | 24 | — |
| 2015 | 4.7L 8-cyl | Premium Gasoline | 24 | — |
| 2014 | 4.7L 8-cyl | Premium Gasoline | 24 | — |
| 2013 | 4.7L 8-cyl | Premium Gasoline | 24 | — |
| 2012 | 4.7L 8-cyl | Premium Gasoline | 24 | — |
| 2011 | 5.5L 8-cyl | Premium Gasoline | 19 | — |
| 2010 | 5.5L 8-cyl | Premium Gasoline | 19 | — |
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