2022 Mercedes-Benz GLE350 — Full Specifications
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The 2022 Mercedes-Benz GLE350 is an SUV powered by a 2L 4-cyl turbo premium gasoline engine. It returns around 26 mpg (UK) / 22 mpg (US EPA) combined. Owners often keep a Mercedes-Benz GLE350 workshop manual to hand for servicing and repairs.
Compared with the 2021 Mercedes-Benz GLE350: Fuel economy is essentially unchanged at around 26 mpg (UK) combined. The engine line-up listed by EPA is unchanged. It carries the same 5★ overall NHTSA rating.
Full Specifications
| Engine | 2L 4-cyl turbo |
|---|---|
| Transmission | Automatic 9-spd |
| Fuel Type | Premium Gasoline |
| Powertrain | Conventional |
| Drive | Rear-Wheel Drive |
| Body Style | SUV |
| Fuel Economy (UK) | 26 combined / 23 urban / 32 extra-urban mpg |
| Fuel Economy (US EPA) | 22 combined / 19 city / 27 highway mpg |
| CO₂ Emissions | 247 g/km |
| EPA Greenhouse Gas Score | 5 / 10 (10 = lowest emissions) |
| EPA Est. Annual Fuel Cost | $3,750 (15,000 mi/yr, US prices) |
Engine & Transmission Options
EPA lists 2 configurations for the 2022 Mercedes-Benz GLE350, all with the 2L 4-cyl turbo engine. The headline figures at the top of this page describe the most fuel-efficient configuration.
| Engine | Transmission | Drive | MPG (UK) | MPG (US) | CO₂ g/km | Fuel cost / yr |
|---|---|---|---|---|---|---|
| 2L 4-cyl turbo | Automatic 9-spd | 4-Wheel Drive | 26 | 22 (19/26) | 250 | $3,750 |
| 2L 4-cyl turbo | Automatic 9-spd | Rear-Wheel Drive | 26 | 22 (19/27) | 247 | $3,750 |
MPG (US) shows combined, with city/highway in brackets. Highlighted row = the configuration used for the headline figures. Source: US EPA fueleconomy.gov.
Owner Essentials for the 2022 Mercedes-Benz GLE350
Running Costs: 2022 Mercedes-Benz GLE350
Covering around 8,000 miles a year in a 2022 Mercedes-Benz GLE350 at 26 mpg combined, expect roughly 1,399 litres of fuel annually — multiply by your local price per litre for a cost estimate. For US owners, the EPA estimates about $3,750 a year in fuel for the most efficient configuration (15,000 miles, national average prices). Work out exact fuel costs with the fuel cost calculator on 247Calculators.
Convert between MPG and L/100km with the unit converters on 247QuickTools. Not sure what tyre size fits? 247TyreCheck explains tyre sizing.
Planning a road trip? Grab a road trip packing list. Only need this car occasionally? See our buy vs rent comparison.
2022 Mercedes-Benz GLE350 Safety Ratings (NHTSA)
Recalls & Owner Complaints (NHTSA)
NHTSA lists no safety recall campaigns for the 2022 Mercedes-Benz GLE350 as of 6 October 2026. Recalls can be issued years after a model is sold, so it is still worth checking your own VIN.
Owners have filed 70 complaints with NHTSA about the 2022 Mercedes-Benz GLE350. The most-reported areas are Engine (21), Electrical system (14), Unspecified (13). Complaints include 2 reported crashes, 1 reported fire, 4 reported injuries. That is close to the median of 63 complaints across the 10 Mercedes-Benz GLE350 model years in our data.
Used-buyer checklist for the 2022 Mercedes-Benz GLE350
Based on where NHTSA recalls and owner complaints cluster for this model year, these are the areas worth checking before you buy:
- Engine (21 owner complaints) — Listen for unusual noise on a cold start, check for warning lights and ask for the service records.
- Electrical system (14 owner complaints) — Test every switch, window, light and warning lamp on a test drive, and ask about battery or alternator replacements.
- Fuel system (8 owner complaints) — Ask whether any fuel-pump or fuel-system recalls were completed, and watch for hard starting or stalling.
Source: US NHTSA recall and consumer-complaint databases, retrieved 6 October 2026. Complaints are unverified owner reports, not confirmed defects. Check any vehicle by VIN at nhtsa.gov/recalls, and see our guide to checking a used car for recalls.
How It Compares
How does the Mercedes-Benz GLE350 compare to similar SUVs? SUVs in our database average around 27 mpg (UK) combined — this model sits close to that average, within 1 mpg. Its 247 g/km CO₂ figure is 6 g/km lower than the 253 g/km average for SUVs on this site. This comparison is based on 1824 SUVs in our dataset.
At 26 mpg (UK) combined it sits close to the 26 mpg average for Mercedes-Benz models in our database. Its 247 g/km CO₂ figure is 21 g/km lower than the 268 g/km Mercedes-Benz average.
Of the 10 Mercedes-Benz GLE350 model years we cover, the 2022 ranks 4th for combined fuel economy on its best configuration (26 mpg UK combined, against a high of 29 mpg). See every Mercedes-Benz GLE350 year side by side.
Last updated: · Data: US EPA (fueleconomy.gov) and NHTSA safety ratings 18 July 2026; NHTSA recalls and complaints 6 October 2026; Wikidata & curated EU catalogue 18 July 2026; European generation and engine data from Wikipedia 7 October 2026
Vehicle data sourced from manufacturer specifications. Always verify with your vehicle handbook or a qualified mechanic. This is a reference tool, not professional advice.
Recommended Accessories for the 2022 Mercedes-Benz GLE350
Frequently Asked Questions
What engine does the 2022 Mercedes-Benz GLE350 have?
It's fitted with a 2L 4-cyl turbo premium gasoline engine, paired with a automatic 9-spd transmission.
What is the fuel economy of the 2022 Mercedes-Benz GLE350?
The most efficient configuration returns around 26 mpg (UK) combined, or 22 mpg on the US EPA cycle.
How much does the 2022 Mercedes-Benz GLE350 cost to fuel per year?
The US EPA estimates about $3,750 a year in fuel for the most efficient configuration, based on 15,000 miles of mixed driving and national average fuel prices. Your own cost will depend on mileage and local prices.
Does the 2022 Mercedes-Benz GLE350 have a good safety rating?
It holds an overall NHTSA rating of 5 stars, with 5 stars for frontal crash protection.
Does the 2022 Mercedes-Benz GLE350 have any recalls?
NHTSA lists no safety recall campaigns for the 2022 Mercedes-Benz GLE350 as of 6 October 2026. Recalls can be issued years after a model is sold, so it is still worth checking your own VIN.
What are the most common problems reported for the 2022 Mercedes-Benz GLE350?
Among the 70 owner complaints filed with NHTSA, the most-reported areas are Engine (21 complaints), Electrical system (14 complaints), Unspecified (13 complaints). Complaints are unverified owner reports, not confirmed defects, and raw counts rise with how many cars were sold.
Is the Mercedes-Benz GLE350's fuel economy good for an SUV?
It returns around 26 mpg (UK) combined, against a same-body-style average of roughly 27 mpg among the SUVs we track.