Mercedes-Benz E350 — All Years
We have Mercedes-Benz E350 specifications on file for 14 model years, 2010–2026, covering saloon/sedan trims. Across those years EPA data lists 2 different engines. Combined fuel economy runs from 23 to 34 mpg (UK) depending on year, engine and transmission. 4 of the 7 rated model years hold an overall 5-star NHTSA rating. Select a year below for full engine, fuel economy, dimensions and safety data.
| Year | Engine(s) | Fuel | MPG (UK) | CO₂ g/km | NHTSA | Recalls | Complaints |
|---|---|---|---|---|---|---|---|
| 2026 | 2L 4-cyl turbo | Premium Gasoline | 32–34 | 196 | — | 0 | 6 |
| 2025 | 2L 4-cyl turbo | Premium Gasoline | 32–34 | 196 | — | 2 | 5 |
| 2024 | 2L 4-cyl turbo | Premium Gasoline | 32 | 203 | — | 0 | 25 |
| 2023 | 2L 4-cyl turbo | Premium Gasoline | 29–31 | 213 | 5★ | 0 | 24 |
| 2022 | 2L 4-cyl turbo | Premium Gasoline | 29–31 | 213 | 5★ | 0 | 22 |
| 2021 | 2L 4-cyl turbo | Premium Gasoline | 30 | 217 | 5★ | 0 | 20 |
| 2020 | 2L 4-cyl turbo | Premium Gasoline | 30–31 | 209 | 5★ | 1 | 24 |
| 2016 | 3.5L 6-cyl | Premium Gasoline | 28 | 234 | 4★ | 0 | 89 |
| 2015 | 3.5L 6-cyl | Premium Gasoline | 28 | 235 | 4★ | 0 | 57 |
| 2014 | 3.5L 6-cyl | Premium Gasoline | 26–29 | 234 | 4★ | 0 | 304 |
| 2013 | 3.5L 6-cyl | Premium Gasoline | 26–28 | 239 | — | 0 | 185 |
| 2012 | 3.5L 6-cyl | Premium Gasoline | 26–28 | 240 | — | 0 | 235 |
| 2011 | 3.5L 6-cyl | Premium Gasoline | 23–24 | 276 | — | 0 | 296 |
| 2010 | 3.5L 6-cyl | Premium Gasoline | 23–25 | 263 | — | 0 | 258 |
Best and Worst Mercedes-Benz E350 Years: What the NHTSA Data Shows
Across the 10 Mercedes-Benz E350 model years from 2010 to 2022 that have NHTSA data, the typical year has about 137 owner complaints on file. These are the extremes:
Fewest owner complaints
Complaint counts are unverified owner reports to NHTSA and rise with how many cars were sold and how long they have been on the road, so treat them as a pointer for what to inspect, not a reliability score. Model years after 2022 are left out because they have had little time to accumulate reports. Always check a specific car by VIN at nhtsa.gov/recalls.
Engine History
- 3.5L 6-cyl — 2010–2016
- 2L 4-cyl turbo — 2020–2026
Engines are those EPA lists for each model year; the MPG (UK) column shows the range across configurations where more than one exists.
Compare the Mercedes-Benz E350 With Rivals
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Frequently Asked Questions
What years is the Mercedes-Benz E350 covered on this site?
We have data for 14 model years of the Mercedes-Benz E350, from 2010 to 2026.
What engines does the Mercedes-Benz E350 come with?
EPA data lists: 3.5L 6-cyl (2010–2016); 2L 4-cyl turbo (2020–2026).
Which Mercedes-Benz E350 year has the best fuel economy?
The 2026 model returns the highest combined MPG (UK) on record here, at 34 mpg on its most efficient configuration.
Does the Mercedes-Benz E350 have a 5-star NHTSA safety rating?
Yes — the 2020, 2021, 2022, 2023 model years hold an overall 5-star NHTSA rating on record here.
Which Mercedes-Benz E350 model years have the most recalls and complaints?
The 2025 model year has the most NHTSA recall campaigns on record (2), and the 2014 has the most owner complaints (304). NHTSA lists no recalls for 2010–2016, 2021–2024 and 2026. Counts are from NHTSA as of 6 October 2026 and change over time; complaints are unverified owner reports.
What body style is the Mercedes-Benz E350?
The Mercedes-Benz E350 is classed as a saloon/sedan on this site.
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